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Even though you may feel good, the longer duration of therapy will insure that you do not get a recurrence of your infection. This effect may have Biaxin due to inhibition of CYP3A4 by itraconazole. Antihistamines Toxic effects of terfenadine and astemizole have been reported in patients taking concomitant Online, especially , typically resulting in prolongation of the QT interval and cardiac dysrhythmias torsade de pointes.

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Torsade de pointes occurred in a 77-year-old woman taking cisapride and clarithromycin. Colchicine Fatal colchicine intoxication occurred in a 67-year-old man who had taken clarithromycin 500 mg bd for 4 days. Clarithromycin may have inhibited colchicine prescription and caused a rise in colchicine concentration. Digoxin Clarithromycin has been reported to cause digoxin toxicity. Two different mechanisms are involved, inhibition of the renal excretion of digoxin and alteration of intestinal flora, which reduces the presystemic hydrolysis of digoxin.

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The effects of fluconazole and clarithromycin on the pharmacokinetics of rifabutin and 25-O-desacetylrifabu-tin have been studied in ten HIV-infected patients who were prescription rifabutin 300 mg qds in addition to fluconazole 200 mg qds and clarithromycin 500 mg qds. Both developed severe hypoglycemia within 48 hours of starting clarithromycin. Steady-state tacrolimus concentrations rose in a 32-year-old African-American man who took clarithromycin 500 mg bd for 4 days.

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